What Can Stem Cell Technology Do With Patients Of Parkinson’s Disease

You might have heard about the alarming situation, which is being prevailed across UK because of the increasing cases of Parkinson’s disease in this part of the world. Right now, the number of patients of this disease is too high in UK. Medical and scientific researchers are working hard to apply stem cell technology on the patients so that they could treat their disease in safe way. It is Oxford Parkinson’s Disease Center, where efforts are being made in the form of advancement in the field of IPS cell technology. They are trying to make their research even better so that they could use this technology safely on Parkinson’s patients. The best part about the advancement in the field of stem cell technology is that this research is being fully supported by public and private sector. Oxford Parkinson’s Disease Center is receiving considerable about of funds and grants, which are being used for the development of skin-cell-to-brain-cell research program.

The work, researches and studies that have been conducted so far, have helped the researchers to know that this disease is caused when dopamine cells are dead in the body. Now, the researchers take skin cells of the patients and then the cells are concerted into induced pluripotent stem cells. These converted cells are later on converted into dopamine neurons, which are helpful and effective for giving the right treatment to the patients. The reason why skin samples are taken instead of doing brain biopsy of Parkinson’s disease patients is that taking samples is easier and safer for the patients. Moreover, this process gives better and accurate results. When the neurons of patients and non patients are taken and compared, then researchers come to know the reasons due to which dopamine neurons die. Now, Wade-Martins and his team are planning something that would support this research like never before. They are planning to use their Monument Discovery Award for the purpose of doing research on IPS cells technology for the coming 5 years.

provide Custom IPS cells – Transposagen’s exclusive technologies piggyback and rat spermatogonial stem cells (SSCs) are utilized to generate custom stem cell technology faster, cheaper and with higher quality than possible by using standard pronuclear injection methods.

Warning Signs Of Alzheimers Disease

Dementia is the loss of brain function, including memory, judgment and behavior. Alzheimers disease is a common form of dementia that is irreversible and progressive. The symptoms of Alzheimers disease go beyond that of normal aging, eventually affecting sufferers ability to perform even the simplest of tasks. As such, those with Alzheimers disease often require dementia care or Alzheimers care, a specialized level of senior care geared toward those with an advanced form of the disease.

The Alzheimers Association has developed 10 warning signs of Alzheimers disease. These warning signs are:

Memory loss Frequently forgetting things, especially things that happened even a few hours before, is one of the most common signs of Alzheimers disease. A person suffering from Alzheimers may ask the same questions or repeat the same stories over and over again.

Difficulty planning or with problem solving – People with Alzheimers may have increased problems with the ability to develop and/or follow complex processes such as budgeting.

Problems completing everyday tasks Someone with Alzheimers disease may have increased difficulty completing ordinary tasks that they did before with ease, such as following a favorite recipe, driving to familiar places or remembering the rules of games.

Language problems – Forgetting and/or substituting the names of everyday objects is an early sign of Alzheimers. For instance, someone with Alzheimers may refer to a car as “that thing that drives.”

Disorientation – People suffering from dementia tend to get confused more often. For example, an Alzheimers sufferer may get lost in a neighborhood theyve lived in for decades.

Impaired judgment Those with Alzheimers may exhibit increasingly poor judgment such as not dressing appropriately for the weather, not keeping up with housekeeping or personal hygiene or spending large amounts of money on things they do not need.

Misplacing things – A person with dementia may start placing objects in odd places, such as a hat in the freezer or jewelry in the dishwasher.

Personality changes A noticeable shift in disposition is a common sign of dementia. Alzheimers sufferers may suddenly become more fearful or passive.

Mood swings Dementia sufferers may experience dramatic shifts in mood from happy to tearful without apparent provocation.

Loss of interest in activities – Someone suffering from dementia may not be as motivated to engage in activities they once enjoyed, spending most of their time sleeping or in front of the TV.

If your loved one is regularly exhibiting one or more of the above signs, please consult with a doctor or physician for a formal diagnosis to receive Alzheimers disease information, care and support as early on as possible.

The Causes Of Diabetic Foot Disease

Diabetic Foot Disease often occurs in winter with a higher risk, especially for elderly patients with Diabetes who should pay special attention to foot care. The incidence of Diabetic Foot Disease in winter is 2.8 times higher than that of other seasons. It is caused by different temperature between indoor and outdoor, leading to increase of vasoconstriction. In winter, the incidence of foot disease in the North is much higher than that in the south. If the Diabetes patients feel cold or numb in hands and feet, they should pay close attention to it because it is likely to be symptoms of Diabetic foot!

What are the causes of Diabetic Foot Disease?

First, Diabetic Chronic Peripheral Vascular Disease. Chronic Peripheral Blood Disease will cause gradual narrowing of vascular lumen, drop of blood pressure in foot and gangrene when there is trauma, infection or climate change. Peripheral vascular disease will cause a series of symptoms such as numbness, pain on lower limbs and short walking distance.

Second, Diabetic Chronic Peripheral Neuropathy. Autonomic Neuropathy often leads to sensory disturbances in food and reduced immunity so that the foot can be hurt easily with ulcers or infections; the manifestations of sensory dysfunction are loss of sensation or abnormal sensation, such as numbness in hands or feet, especially in feet, feeling like walking on cotton, or pins and needles.

Third, when vascular disease and neuropathy appear on Diabetic patients, if their shoes, socks are too tight or toenails are too long, it can cause foot skin damage and then occurrence of Diabetic Foot Disease. If it cant be handed in time or improperly, it will further develop into ulcers.

What are the latest developments in treatment of Diabetic Foot Disease? Recently, the medical community has introduced the most advanced technology of Stem Cell Transplant to treat Diabetic Foot Disease. After stem cells are transfused into the patients body, they will stimulate vascular endothelial growth factors to promote their proliferation and propagation and angiogenesis in lower limbs. As a result, it can improve the condition of ischemia and hypoxia on lower limbs and promote wound healing to avoid the danger of amputation. At the same time, stem cells can repair damaged pancreas islet and pancreatic islet cells to recover their function and then cure Diabetic Foot Disease.

Dr. Michael Har-Noy Says Cancer Is NOT A Disease of Weakened Immunity

Dr. Michael Har-Noy of Immunovative Therapies, a biotech company founded in Israel in 2004, says that a common misconception is that cancer is a disease of the weakened immune system.

Dr. Michael Har-Noy explains that when a normal cell becomes a tumor cell, changes occurring in the expression of surface antigens give rise to tumor associated antigens (TAAs) that theoretically could be detected by one’s immune system. Ehrlich, in 1909, first proposed that one’s immune system protected against cancer, a concept adapted in the 1950s by Lewis Thomas and then later by Sir Macfarlane Burnet, who proposed that a patient’s immune system had a -surveillance- mechanism for tracking down and killing precancerous and cancerous cells. The basis of this hypothesis is that tumors constantly arise in one’s body and that one’s immune system must recognize and destroy cells that have TAAs on their surface.

This theory goes on to predict that in cases where the patient’s immune system is suppressed, the surveillance mechanism is then compromised, and the cancer cells grow out of control and clinical disease becomes detectable. This is the theory behind the concept that the patient’s immune system in cancer cases is weak, and that this immune system must be reinforced to attack the cancer effectively.

Dr. Michael Har-Noy and Immunovative Theories believe that there is, however much evidence to the contrary. While a small number of the rarer cancers occur in immune compromised individuals, most human malignant tumors are found in patients with intact immune systems. Also, many cancers, especially epithelial cell tumors, have a significant component of inflammatory cells. This includes diverse leukocyte infiltrates of macrophages, neutrophils, eosinophils, and mast cells, frequently in the presence of lymphocytes. Malignant tumors are typically densely infiltrated with immune cells, which argues against inadequate immune system recognition of TAAs.

Furthermore, many previous attempts to bolster the normal immune response enhanced rather than suppressed growth of the cancer. For example, in mice, a newly induced tumor of both mesenchymal and epithelial origin grows faster if it precipitates a reaction from the patient’s immune system. Highly immunogenic cancers left undisturbed in their original hosts often grow faster than tumors that stimulate little or no immune response. Therefore, the idea that tumors are -invisible- to the patient’s immune system and that this immune system needs to be augmented appears to be incorrect.

The problem may be that the patient’s immune response to the tumor is the wrong kind of response. Dr. Michael Har-Noy and his team at Immunovative Theories believe that in attempting to boost an immunologic response that has already failed to protect the patient against cancer, tumor growth may be enhanced rather than suppressed. This is probably why most immunologic cancer treatments to date have been ineffective.

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Scientists look for clues behind mad-cow disease

It may seem odd, but scientists are studying a bovine disease-mad-cow disease-to find new ways to treat Alzheimer’s, Parkinson’s, and Lou Gehrig’s disease. The reason for scientists to believe there is a connection (a common thread) between these diseases, is that each neurodegenerative disorder is caused by aberrant proteins that travel from cell to cell-effectively destroying whatever cell is in its way. This article was provided by Chicagoland Methodist Senior Services, a Chicago Home Care Agency .

When normal cells are met by a deformed protein, normal function of that cell comes to a screeching halt which leads to a neurological issue. The causes of these issues are similar in theme among Alzheimer’s, Parkinson’s, Lou Gehrig’s and you guessed it: mad-cow. There are other diseases linked to deformed proteins (like Type 2 diabetes) but the difference is in diseases that damage brain activity, the deformed proteins are inclined to induce deformity in other proteins.

Theses deformities in proteins cannot be reversed, so the thought is that to find a cure for these diseases would involve stopping the deformed proteins from spreading to other healthy proteins. In a sense, what damage is done-is done-but by effectively halting this migration of deformed proteins to other proteins, the progression of the brain damage would be prevented. In diseases like Alzheimer’s, it’s thought that a tactic of such could be a solution to slow, stop, or even prevent occurrences of this disease.

In healthy proteins in our body, there is a process called folding where the cell takes a three-dimensional shape. This shape is what allows the protein to function normally-to carry out its duty to the body. When a protein is prevented from folding, it can become toxic. In a young body, there is a defense system to rid these toxic proteins from the body, but as the body ages, its ability to defend itself is weakened, thus less effective against said proteins. In diseases like Alzheimer’s, these toxic proteins travel to other healthy proteins causing them to misfold. This misfolding extinguishes normal function.

As mice are used for experimentation, further discoveries are made to conclude how prion diseases-diseases that cause neurological disorders-function. In one case study, mice were injected with a synthetic version of a deformed protein. Just like proteins associated with Alzheimer’s or Parkinson’s, the synthetic protein passed from healthy protein to healthy protein causing crucial neurons in the mice’s brains to die. The deaths of these proteins lead to symptoms very similar to neurological diseases in humans.

Now, scientists are studying antibody therapy that could stop toxic proteins from moving to other healthy proteins. If the therapy works in mice, one day this type of therapy could be tested in humans.

What Are The Causes And Effects of Congenital Heart Disease

Congenital heart disease is far more widespread than most people realize. The heart is the most significant organ of ones body; it ensures blood circulation all through the body, without which life would not be possible. Medicine has advanced greatly and, with contemporary technology, almost all heart diseases can be treated successfully if detected in time.

What is Congenital Heart Disease

Congenital heart disease, or CHD, is a malformation of the heart or a great blood vessel near the heart. Congenital heart disease is a condition that one is born with and it is one of the the most familiar forms of major birth defects in newborns, affecting approximately 8 of congenital heart disease cases.

This condition is not a issue until after birth, as the blood circulation differs from that ensuing birth. The fetal circulation derives oxygen and nutrients from the mother around the placenta, and the fetal circulation has important communications between the upper heart chambers and the great blood vessels near the heart. As such, most types of congenital heart disease are well tolerated during fetal life.

The Causes of Congenital Heart Disease

This disease can have many different causes like:

Environmental elements such as chemicals or drugs are sometimes to blame. For example, if a mother-to-be catches measles or rubella during pregnancy, the infection can impair the perfection of the unborn babys heart or other organs. Similar effects can be observed if the mother-to-be consumes alcohol during pregnancy.

Maternal diseases for the mother can also increase the risks of developing congenital heart disease in the unborn baby.

Chromosome abnormalities – A typical chromosome abnormality causing congenital heart disease is Downs syndrome where an extra #21 chromosome is present. About 50% of children with Downs syndrome also carry CHD.

Treating Congenital Heart Disease

The treatment depends from patient to patient owing to the huge difference in occurrence from case to case. Everything needs to be taken into consideration to allow for an effective treatment program. A treatment program can only be determined after correct diagnosis from a specialist. While eating healthy and exercising usually helps, congenital heart disease is a unique case which needs to follow strict gps instructions; no self medication or treatment is advised.

Knowledge and guidelines are available both online and in the medical practitioners office to help one educate themselves to deal better with congenital heart disease.

Effective Alternative Methods Of Treating Lyme Disease

Although antibiotics have been proven effective in treating Lyme disease, many other alternative methods of treatment should be used. These natural medicines are safe and fast cures for Lyme disease, even if it is very old. For a speedy recovery, these are the different treatments for Lyme disease:

Try using cat’s claw

It is observed by some doctors that Samento or una de gato, also known as Cat’s claw, helps treat Lyme disease. A herbal medicine is manufactured from the extract of cat’s claws’ inner bark and is said to act as an antimicrobial therapeutic agent. Borrelia organisms, which cause Lyme disease, will be killed by this treatment, and even the neuropathic symptoms of Lyme disease will go away. It is most effective when used with other digestive enzymes and detoxifying medication to treat Lyme disease.

Homeopathic treatments

Homeopathic remedies are a form of alternative medicine directed to a specific illness or condition using specific diluted preparations. Not all of the remedies address the same stage of Lyme disease. They can be used along with antibiotics prescribed by your physician. Each brand offers different dosages and frequencies. Below is an example:

From week one to week four after the tick bite: Propolis formula made up of Propolis resin, Echinacea root, Red root, and Licorice root.

From week one to week five after the tick bite: Lomatium formula made up of Lomatium root, Witch hazel, Elderberry, and Prickly ash.

From 6 months onwards after the tock bite: Waltheria formula made up of Waltheria root, Osha root, American Ginseng root, and Artemesia annua.

Eat more garlic

Garlic is considered to be a universal antibiotic. You can support and improve your immune system, as well as battling the Borrelia bacteria and supporting your Lyme disease treatment, by increasing the amount of garlic you eat.

African herbs

Lyme disease is known to be treated by the help of some African herbs like African Potato extract or Hypoxis Rooperi and Buchu or Agathosma Betulonia. They helps in boosting your immune system, and they act as natural agents for restoring your health.

Consuming probiotic-rich foods

Although not really an alternative treatment for Lyme disease, eating foods rich in probiotics, such as yogurt and kefir, will help protect you from gastrointestinal problems brought on by antibiotic intake. Probiotics contain good bacteria that can stimulate your immune system, helping you quickly recover from Lyme disease.

Eating foods rich in Vitamin C

Your immune system is enhanced by vitamin C. Eating foods rich in Vitamin C can help relieve the flu-like symptoms of Lyme disease quickly. Examples of such foods include citrus fruit, red pepper, guava, papaya, and many other fruits and vegetables.

Physicians are researching other natural remedies that are available for treating Lyme disease. In general, these herbs are the most effective when taken with antibiotics and will help subdue the side effects of antibiotics.